News & Press Coverage
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December 18, 2020
LSI sends off Dr. Miller and Dr. Dahotre
Congratulations to Ian Miller and Shreyas Dahotre for being the first two graduate students to leave the lab as Ph.D.'s! Ian will be working as a Research Scientist for Intellia Therapeutics in Cambridge, MA, and Shreyas will be working as a Research Scientist for Obsidian Therapeutics in Cambridge, MA. LSI wishes you best of luck! -
October 14, 2020
LSI goes to BMES 2020
Congratulations to these students who delivered podium talks at the 2020 BMES Virtual Annual Meeting: Quoc Mac – “Activity Sensors for Monitoring Therapeutic Response and Illuminating Resistance Mechanisms during Immune Checkpoint Immunotherapy” Lena Gamboa – “Sensitizing solid tumors to CAR T cell-mediated cytotoxicity using synthetic antigens” Anirudh Sivakumar – “Logic-Gated Protease Sensors for Non-Invasive Monitoring […] -
October 7, 2020
‘Programmable Medicine’ is the Goal for New Bio-circuitry Research
In the world of synthetic biology, the development of foundational components like logic gates and genetic clocks has enabled the design of circuits with increasing complexity, including the ability to solve math problems, build autonomous robots, and play interactive games. A team of researchers at the Georgia Institute of Technology is now using what they’ve […] -
October 6, 2020
Protease circuits for processing biological information published in Nature Communications
Our work on engineering biological circuits was published in Nature Communications! Congratulations to Brandon and the team! Read the full manuscript here. Summary | Biological circuits engineered to interface with living systems will enable new applications for programmable immune therapies and diagnostics. In this study, we explored how treating proteases as 'biological bits' could be […] -
September 4, 2020
LSI welcomes graduate student Aaron Silva Trenkle
Aaron Silva Trenkle joins LSI as a new graduate student. Aaron completed his bachelors at the University of Iowa in BME and minored in German. Aaron was part of two labs at UIowa and spent two summers performing research in Germany through the DAAD RISE program. Read more about Aaron here. -
September 1, 2020
Kelsey Kubelick joins LSI as a post-doctoral fellow
Kelsey Kubelick joins LSI as a new post-doc. Kelsey is originally from Pittsburgh, PA. She completed her Ph.D. in biomedical engineering at Georgia Tech in 2020 with Dr. Stanislav Emelianov in the Ultrasound Imaging and Therapeutics Research Lab. Her dissertation research focused on developing photoacoustic imaging methods to track cells and particles. Read more about […] -
July 14, 2020
Shreyas Dahotre defends Ph.D. thesis
Congratulations to Shreyas Dahotre for becoming the second LSI Ph.D. graduate! Shreyas successfully defended his thesis, titled “Programmable Immune Cytometry and Diagnostics,” in front of a virtual crowd on July 14, 2020. We look forward to your future success! -
June 23, 2020
Ian Miller defends Ph.D. thesis
Congratulations to Ian Miller for being the first Ph.D. graduate from LSI! Ian successfully defended his thesis, titled “Remote control of CAR T cell therapies by thermal targeting,” in front of a virtual crowd on June 23, 2020. We look forward to your future success! -
May 20, 2020
LSI undergrads McKenzie Tuttle, Melanie Su, and Haley Liakakos part of winning team at EGHI/GT HACK COVID-19
Congratulations to McKenzie, Melanie, Haley, and the rest of their team for their winning app at EGHI/GT HACK COVID-19! The team developed CAPACIT, an app that communicates current population density at businesses to potential shoppers. Users can plan their day from live updates on current capacity of public spaces through the app. Watch their pitch […] - May 1, 2020
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March 31, 2020
Anna Romanov named NSF Graduate Fellow
Congratulations to Anna for winning a fellowship from the NSF GRFP! The NSF Graduate Research Fellowship Program recognizes and supports outstanding graduate students in NSF-supported science, technology, engineering, and mathematics disciplines. Read more here. -
March 27, 2020
Kevin Tao wins Barry Goldwater Scholarship
Congratulations to Kevin Tao for receiving a 2020 Barry Goldwater Scholarship! The Goldwater Scholarship is the preeminent undergraduate award for outstanding students pursuing careers in the fields of mathematics, the natural sciences, and engineering. Goldwater Scholars have been awarded 92 Rhodes Scholarships, 137 Marshall Awards, 159 Churchill Scholarships, 104 Hertz Fellowships, and numerous other distinguished […] -
March 26, 2020
Dr. Kwong promoted to Associate Professor with Tenure
Gabe Kwong Promoted to Associate Professor with Tenure Kwong’s lab pioneers powerful new technologies to address frontier clinical challenges – including ultrasensitive diagnostics for early detection of disease, engineered T cells as curative therapies, and high-throughput tools to study rare immune cells. His research directly impacts a broad range of complex human diseases including cancer, […] -
March 18, 2020
Dr. Kwong wins 2020 Sigma Xi Best Faculty Paper Award
Our paper on developing synthetic biomarkers for non-invasive early detection of organ transplant rejection won the 2020 Sigma Xi Best Faculty Paper Award at Georgia Tech. Congrats to Gabe and to Quoc for spearheading the research! Read the announcement from the BME Department here. -
March 2, 2020
Gabe Kwong named a 2020 TEDMED Hive Innovator
Recognizing & Celebrating the Innovation Powering a Healthier World Progress towards a healthier world begins with individuals who are willing to break the limits of convention, and to challenge the status quo. These innovators embrace imagination and aren’t afraid to explore both chaos, clarity, and the space between in order to discover new paths to […] -
February 19, 2020
Review on remote control in synthetic immunity published in Theranostics
Our review on the opportunities, challenges and the current state-of-the-art for remote control of immune cells to increase treatment precision and safety profile is published in Theranostics! Congrats to Lena and Ali! Read the manuscript here. -
February 10, 2020
Ian Miller presents work at Keystone Symposium
Ian traveled to Banff, Canada to present his work at a poster presentation at the “Emerging Cellular Therapies: Cancer and Beyond” Keystone Symposium. Meeting Summary: After many years of fundamental research, cell-based therapies are now recognized as effective medicines for treatment of a specific subset of cancers as well as a growing list of autoimmune, […] -
January 6, 2020
Remote control of dCas9 to modulate cell function published in ACS Chemical Biology
Our work on heat-triggered remote control of CRISPR-dCas9 for tunable transcriptional modulation was published in ACS Chemical Biology! Congratulations to Lena and the rest of the team! Read the full manuscript here.Summary | CRISPR-based approaches have achieved wide success in modulating gene activity to control cell function and are potential tools for clinical therapies. However, the […] -
October 25, 2019
Hyoungjun Sim and Henry Zhao win PURA Salary Awards
Congratulations to Jun and Henry for winning a President’s Undergraduate Research Awards (PURA) for Spring 2020! PURA fund student salaries to conduct undergraduate research with Georgia Tech faculty and offset travel expenses for undergraduates to present their research at professional conferences. Between two hundred and three hundred competitive awards are offered on campus each year. […] -
October 17, 2019
Kevin Tao and Fang-Yi Su selected for the Petit Scholars Program 2020
Kevin has been selected as a Petit Undergraduate Scholar for 2018 with Ida serving as his Petit Mentor. Congratulations! From the Petit Institute for Bioengineering and Bioscience, “The Petit Undergraduate Research Scholars program is a competitive scholarship program that serves to develop the next generation of leading bioengineering and bioscience researchers by providing a comprehensive […] -
October 3, 2019
Ian presents at Fred Hutch Cancer Center, Seattle
Grad student Ian Miller presented his work on thermal control of CAR T cells at the Fred Hutch Immuno-Oncology Graduate Student Symposium hosted by Fred Hutch’s Immunotherapy Integrated Research Center (IIRC). Participants were able to meet faculty, learn about the breadth of research done in immuno-oncology, visit research laboratories and shared resource facilities, and tour […] -
September 23, 2019
Noina Phuengkham joins LSI as a post-doctoral fellow
Hathaichanok “Noina” Phuengkham joins LSI as a new post-doc. Noina originally hails from Thailand and completed her Ph.D. studies at Sungkyunkwan University in South Korea where she developed biomaterials to alter immunosuppressive tumor microenvironments with Dr. Yong Taik Lim. Read more about Noina here. -
September 18, 2019
Dr. Kwong delivers invited lecture at Transplant Immunosuppression 2019
Dr. Kwong was invited to speak at the Transplant Immunosuppression 2019 Conference in Minneapolis, MN. The course focused on current options for immunosuppression (and what’s in the pipeline), with particular attention to individualization of immunosuppression based on clinical and/or laboratory parameters; prevention, diagnosis and treatment of antibody-mediated rejection; improving long-term transplant outcomes; and major issues […] -
September 13, 2019
LSI welcomes graduate student Ali Zamat
Ali was raised in San Diego, CA before moving to São Paulo, Brazil for three years. He attended UCSD where he graduated summa cum laude with a B.S. in Bioengineering. As an undergraduate, he developed a STEM immersion program for a local high school. In the lab, Ali investigated new drug delivery techniques to reduce […] -
September 3, 2019
New study with the Qiu Group published in PloS Computational Biology
Our work with the Qiu group is now online in PLoS Computational Biology! The activity of enzymatic proteins, which are called proteases, drives numerous important processes in health and disease: including cancer, immunity, and infectious disease. Many labs have developed useful diagnostics by designing sensors that measure the activity of these proteases. However, if we […] -
August 22, 2019
LSI awarded talks at BMES 2019
Multiple students were awarded podium talks at the 2019 BMES Annual Meeting in Philadelphia, PA. They are: Brandon Holt – “Synthetic biological circuits for treating prodrug-resistant bacteria” Brandon Holt – “Proteases as biological bits for programmable medicine” Ian Miller – “Remote Control of CAR T Cells Using Thermal Cues” Shreyas Dahotre – “Ultrasensitive Detection of […] -
July 30, 2019
Dr. Kwong part of NCI Think Tank discussing early cancer detection
Dr. Kwong was invited to participate in the Synthetic Biomarkers for Detection of Cancers at Incipient and Early Stages (SYNDICATE) Think Tank Meeting hosted by the Division of Cancer Prevention (DCP) at the National Cancer Institute (NCI), and co-chaired by Dr. Sangeeta Bhatia, Massachusetts Institute of Technology, and Dr. Sam Gambhir, Stanford University. The think tank […] -
July 16, 2019
Adrian Harris joins LSI as Research Technician
Adrian was born in Dover, Delaware but spent half of his life in Dahlonega, GA. He graduated cum laude from the University of Georgia, where he received a B.S. in Biochemistry and Molecular Biology. During his undergraduate years, he worked in Dr. Amy Medlock’s laboratory, investigating the regulatory roles of Peroxiredoxin 5 and Progesterone Receptor […] -
July 11, 2019
LSI awarded NSF grant to develop cell sorting technologies
LSI awarded $500,000 from the NSF Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) for "Ultra-fast transient cell adhesion and its application for high-throughput microfluidic cell sorting". Our co-PI's are Dr. Alexander Alexeev (associate professor, The George W. Woodruff School of Mechanical Engineering) and Todd Sulchek (professor, The George W. Woodruff School of Mechanical […] -
July 2, 2019
LSI wins seed grant from the Petit Institute
The labs of Gabe Kwong (assistant professor, Coulter Department of Biomedical Engineering) and M.G. Finn (professor, School of Chemistry and Biochemistry) were awarded a grant for “Activity biosensors that implement Boolean logic as precision diagnostics for immunotherapy.” The researchers reason that disease detection and evaluation of treatment responses in vivo depend on the ability to extract clinically […] -
June 28, 2019
LSI part of multi-institute effort to develop new treatments for influenza infection
The Laboratory for Synthetic Immunity is part of a $21.9 million award from DARPA to develop gene therapies to enable protection against a wide range of influenza strains and improve immune responses and efficacy of current influenza vaccines. The work, led by Phil Santangelo at Georgia Tech, is being performed by researchers at GT, Duke, […] -
June 6, 2019
Anna Romanov named Astronaut Scholar
Congratulations to Anna for winning an Astronaut Scholarship from the Astronaut Scholarship Foundation (ASF). In 2019, ASF awarded 52 scholarships to students from 38 different universities across the nation. Astronaut Scholarships are awarded to students in their junior and senior year of college studying science, technology, engineering, or mathematics with the intent to pursue research […] -
May 5, 2019
Lena Gamboa presents work at Synthims 2019
Lena traveled to Ascona, Switzerland to present her talk “Heat-triggered CRISPR-dCas9 for the remote control of therapeutic T cells” at Synthims 2019. The conference covered insights in therapeutic protein engineering, rational vaccine design and delivery; advances in single-cell sequencing and microfluidics as related to the adaptive immune system; adoptive immune cell transfer therapies; and cancer […] -
April 30, 2019
Lee-Kai Sun wins Barry Goldwater Scholarship
Congratulations to Lee-Kai Sun for receiving a 2019 Barry Goldwater Scholarship! The Goldwater Scholarship is the preeminent undergraduate award for outstanding students pursuing careers in the fields of mathematics, the natural sciences, and engineering. Goldwater Scholars have been awarded 92 Rhodes Scholarships, 137 Marshall Awards, 159 Churchill Scholarships, 104 Hertz Fellowships, and numerous other distinguished awards […] -
April 3, 2019
LSI awarded R01 to develop activity sensors to monitor immunotherapy efficacy
LSI has received a $1.8 million grant from the National Cancer Institute at the National Institutes of Health to develop activity sensors to monitor responses to cancer immunotherapy! This work will expand our sensor platform, which has already been used to detect thrombosis, liver fibrosis, cancer, and organ transplant rejection. Read more about this work […] -
March 29, 2019
Isabel Curro wins PURA Award
Congratulations to Mimi for winning a PURA Award! President's Undergraduate Research Awards fund student salaries to conduct undergraduate research with Georgia Tech faculty and offset travel expenses for undergraduates to present their research at professional conferences. -
March 6, 2019
Nanosensors for transplant rejection highlighted in Nature Reviews Nephrology
Our recently published paper in Nature Biomedical Engineering was highlighted in Nature Reviews Nephrology! -
February 18, 2019
Early detection of organ transplant rejection using urine tests published in Nature Biomedical Engineering
Our work on activity sensors for early and noninvasive detection of acute transplant rejection was just published in Nature Biomedical Engineering! Congrats to Quoc and the team! Summary | The current diagnostic “gold” standard to monitor transplant patients for signs of organ rejection is the tissue biopsy. However, this procedure is invasive and lacks the ability to […] -
February 11, 2019
Glympse Bio selected as ‘Fierce 15’ for 2018
FierceMedTech has named Glympse Bio, co-founded by LSI director Dr. Gabe Kwong, as one of its Fierce 15 for 2018. Each year FierceMedTech spotlights 15 of the most innovative and promising startups in the medtech industry. Read more about what makes Glympse fierce here and here. -
January 26, 2019
Brandon Holt presents at Gordon Research Seminar
Brandon gave a podium talk titled "Biological Bits for Computing Classical and Quantum-Inspired Algorithms" at the Complex Active and Adaptive Material Systems Gordon Research Seminar in Ventura, CA. This conference was focused on formulating new ways to inscribe the vital functions found in biological systems into synthetic materials and complex structures. Congrats Brandon and great to […] -
January 24, 2019
Dr. Kwong highlights work on protease sensors for NASH at Keystone Symposium
The global prevalence of nonalcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) has risen precipitously over the past two decades in parallel with the worldwide obesity epidemic, and these diseases are associated with progressive fibrosis and an increased risk of liver cancer. The field lacks an integrated understanding of risk prediction, pathogenesis and validated […] -
January 18, 2019
Detecting antigen-specific T cells with DNA barcoded tetramers published in Analytical Chemistry
Our work on synthesizing DNA-barcoded pMHC tetramers to detect single antigen-specific T cells by ddPCR was published in Analytical Chemistry! Congrats to Shreyas and the team!Read the full manuscript here. -
December 3, 2018
LSI awarded grant from the DARPA PREPARE Program
LSI is part of a team of researchers from Georgia Tech, Emory, Duke, Rockefeller, and UGA that has been awarded funding from DARPA for ‘Thwarting Influenza with RNA-powered Modulators (ThIRM)’. The DARPA PReemptive Expression of Protective Alleles and Response Elements (PREPARE) program is aimed at delivering a capability to generate programmable gene modulator MCMs (PGM-MCMs) […] -
September 21, 2018
Dr. Kwong gives talk at nanoDDS 2018
The 16th International Nanomedicine and Drug Delivery Symposium highlights new groundbreaking discoveries and developments in nanomedicine and drug delivery. Revolutionary advances in this area require collaboration amongst researchers working in a diverse array of fields including nanotechnology, materials science, imaging, cell biology, tissue engineering, gene editing, drug and gene delivery as well as clinical research. […] -
September 17, 2018
Anirudh Sivakumar joins LSI as a new graduate student
Anirudh grew up in Dallas, TX. His love for chemistry and tenure as a mathlete spurred him to graduate from the University of Texas at Austin summa cum laude with a B.S. in Chemical Engineering and a B.S. in Mathematics. As a Cockrell Engineering Honors Scholar, Anirudh worked in Dr. Lydia Contreras’ lab, investigating the effects of […] -
September 12, 2018
Dr. Kwong invited to speak at Northwestern University
Dr. Kwong will be giving a seminar at Northwestern University in the Department of Biochemistry and Molecular Genetics on Sept. 13. His talk is titled “Harnessing Protease Activity as ‘Biological Bits’ for Programmable Medicine”. -
September 1, 2018
Ida Su joins LSI as a post-doctoral fellow
Fang-Yi “Ida” Su joins LSI as a new post-doc. Ida originally hails from Taiwan and came to the United States to complete her Ph.D. studies at University of Washington, where she developed polymeric antibiotic prodrugs for pulmonary bacterial infections with Prof. Patrick Stayton. Read more about Ida here. -
July 16, 2018
Learn how we synthesize protease nanosensors with our latest JOVE publication
Brandon walks through the synthesis of iron oxide nanosensors in our latest publication in JOVE. Watch the video here. -
July 13, 2018
Precisely Targeting Tumors with Cancer-Fighting T Cells
Our work on remote control T cells for cancer immunotherapy was recently published in ACS Synthetic Biology! Engineered T cell therapies are a new class of treatments that have the potential to cure patients of cancer. However, tumors have the uncanny ability to turn off T cells to evade being targeted. In our study, we […] -
July 5, 2018
LSI goes abroad: 4th Paris NASH Meeting!
Dr. Kwong traveled to the Institut Pasteur in Paris, France to talk about work from our lab and Glympse Bio at the 4th Paris NASH Meeting. His talk was titled “Protease activity signatures in NASH”. The Paris NASH Meeting is an international academic meeting is aimed to do a deep-dive into many aspects of NASH and […] -
June 28, 2018
Kevin Tao and Lee-Kai Sun win undergraduate research awards
Congratulations to Kevin and Lee-Kai for winning awards from the Alfred H. Gibeling Family Research Fund through the Biomedical Engineering department to conduct undergraduate research! -
June 26, 2018
Dr. Kwong awarded new patent
Dr. Gabe Kwong at GT/Emory and Dr. Sangeeta Bhatia at MIT have been granted a patent on using isotope-encoded reporters for multiplexed detection of target analytes in biological samples. Congrats! Read more about the patent here. -
June 5, 2018
LSI chosen to give plenary talk at American Transplant Congress 2018
Work in our lab on using synthetic biomarkers to noninvasively detect the onset of acute transplant rejection, spearheaded by graduate student Quoc Mac, was chosen as a plenary talk at the 2018 American Transplant Congress in Seattle, WA. We are excited to share our technology with scientists and clinicians around the country and world! ATC […] -
May 25, 2018
Kevin Tao and Lee-Kai Sun win PURA Salary Awards
Congratulations to Kevin and Lee-Kai for winning a President’s Undergraduate Research Awards (PURA) for Fall 2018! PURA fund student salaries to conduct undergraduate research with Georgia Tech faculty and offset travel expenses for undergraduates to present their research at professional conferences. Between two hundred and three hundred competitive awards are offered on campus each year. […] -
April 3, 2018
Brandon Holt awarded NSF Graduate Fellowship
Congratulations to Brandon for winning a NSF Graduate Fellowship! The NSF Graduate Research Fellowship Program recognizes and supports outstanding graduate students in NSF-supported science, technology, engineering, and mathematics disciplines. -
March 26, 2018
Remote control using heat-triggered gene switches published in ACS Synthetic Biology
Our work on engineering thermal gene switches for spatial and remote control of transcriptional activity in mammalian cells using pulses of heat was published in ACS Synthetic Biology! Congrats to Ian and the team! Read the entire manuscript here. Summary | Genetically engineered T cells have the potential to cure patients of cancer. Yet after they are […] -
March 22, 2018
Anna Romanov wins PURA Salary Award
Congratulations to Anna for winning a President's Undergraduate Research Award (PURA) for Summer 2018! PURA fund student salaries to conduct undergraduate research with Georgia Tech faculty and offset travel expenses for undergraduates to present their research at professional conferences. Between two hundred and three hundred competitive awards are offered on campus each year. Read more about […] -
March 20, 2018
DNA gated cell sorting published in PNAS
Our work on developing DNA gates for multiplexed cell sorting was published in PNAS! Congratulations to Shreyas and the rest of the team!Read the full manuscript here. -
March 16, 2018
Dr. Kwong wins Georgia Tech Teaching Award
Gabe Kwong Honored by Georgia Tech’s Center for Teaching and Learning Gabe Kwong, assistant professor, will receive the Center for Teaching and Learning/BP America Junior Faculty Teaching Excellence Award. Kwong investigates cancer nanotechnology, engineering immunity, biomedical nanosystems, and high-throughput biotechnologies. Here is some of the feedback received from students regarding Kwong’s teaching: “One of the best […] -
February 22, 2018
LSI awarded a grant from The Shurl and Kay Curci Foundation
LSI has been awarded a grant from The Shurl and Kay Curci Foundation for “Enhancing T Cell Therapies for Cancer using Pulses of Heat”. The Shurl and Kay Curci Foundation supports science based research in the areas of neuroscience/brain science, regenerative medicine, cell biology, cancer, and nanotechnology/nanoscience, and strives for the advancement of a healthy […] -
November 6, 2017
Justin Kahla and Quoc Mac selected for the Petit Scholars Program 2018
Justin has been selected as a Petit Undergraduate Scholar for 2018 with Quoc serving as his Petit Mentor. Congratulations! From the Petit Institute for Bioengineering and Bioscience, “The Petit Undergraduate Research Scholars program is a competitive scholarship program that serves to develop the next generation of leading bioengineering and bioscience researchers by providing a comprehensive […] -
October 12, 2017
Congratulations to Lena for winning the Sloan Fellowship!
This fellowship is sponsored by the Alfred P. Sloan Foundation and seeks to increase the number of outstanding engineering Ph.D. graduates from under-represented populations. She was nominated by the director and faculty of Georgia Tech's University Center for Exemplary Mentoring (UCEM). Congrats! -
September 11, 2017
LSI welcomes its first postdoctoral fellow, James Bowen!
James grew up in Rochester, NY and graduated summa cum laude with a B.S. in Biotechnology from SUNY Upstate Medical University in 2011. James spent the next two years as a research technician at the University of Rochester Medical Center in the laboratory of Dr. James Palis, where he studied hematopoietic stem and progenitor cell […] -
July 26, 2017
Lena Gamboa Featured in Brown Engineering Magazine
NSF Fellowship, Brown Connections Lead Marielena Gamboa Castro ’15 to Cancer Research -
June 27, 2017
Gabe Kwong Invited to Join Nation’s Brightest Young Engineers at 2017 US Frontiers of Engineering Symposium
Gabe Kwong, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory, is one of only 82 people selected to participate at the 2017 US Frontiers of Engineering symposium. The symposium, organized by the National Academy of Engineering, gathers what the academy calls “exceptional” engineers from 30 to 45 […] -
June 9, 2017
Justin Kahla and Jason Weis win PURA Salary Awards
Congratulations to undergraduates Justin Kahla and Jason Weis for winning President's Undergraduate Research Awards (PURA)! PURA fund student salaries to conduct undergraduate research with Georgia Tech faculty and offset travel expenses for undergraduates to present their research at professional conferences. Between two hundred and three hundred competitive awards are offered on campus each year. Read […] -
May 22, 2017
Lena Gamboa Castro named NSF Graduate Fellow
Congratulations to Lena for winning the NSF GRFP! The NSF Graduate Research Fellowship Program recognizes and supports outstanding graduate students in NSF-supported science, technology, engineering, and mathematics disciplines. Read more here. -
March 17, 2017
Quoc Mac awarded NSF Fellowship
Congratulations to Quoc for being named an NSF Fellow! The NSF Graduate Research Fellowship Program recognizes and supports outstanding graduate students in NSF-supported science, technology, engineering, and mathematics disciplines. Read more here. -
January 30, 2017
Hassan Fakhoury and Quoc Mac selected for the Petit Scholars Program 2017
Hassan has been selected as a Petit Undergraduate Scholar for 2017 with Quoc serving as his Petit Mentor. Congratulations! From the Petit Institute for Bioengineering and Bioscience, “The Petit Undergraduate Research Scholars program is a competitive scholarship program that serves to develop the next generation of leading bioengineering and bioscience researchers by providing a comprehensive […] -
October 4, 2016
LSI wins $1.5M NIH Director’s New Innovator Award
NIH announces funding for 88 awards on high-impact biomedical research Gabe Kwong, assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory, was named a recipient of the National Institutes of Health (NIH) New Innovator Award on Oct. 4. The High-Risk, High-Reward Research (HRHR) program, supported by the National Institutes […] -
July 17, 2016
LSI members awarded talks at the BMES 2016 Annual Meeting
Several members of LSI were selected to oral presentations at the BMES 2016 Annual Meeting in Minneapolis, MN. They are as follows: Dr. Gabe Kwong – “A Mathematical Framework for Ultra-sensitive Detection of Cancer Using Activity-Based Biomarkers” Shreyas Dahotre – “Highly Multiplexed Analysis of Cancer-specific T cells using DNA-barcoded peptide-MHC Tetramers” Ian Miller – “Engineering […] -
July 5, 2016
LSI welcomes MD/PhD student Yun Min Chang
Yun Min “Danny” Chang joins LSI as a graduate student co-advised with Dr. Rafi Ahmed at Emory. Danny was born in Seoul, South Korea and immigrated to the US at the age of 9. He grew up in Tarpon Springs, FL and graduated summa cum laude with a B.S. in Chemistry at the University of Florida. As […] -
June 5, 2016
Oliva Delmas joins LSI as a lab technician
The Laboratory of Synthetic Immunity welcomes Oliva as a lab tech. Olivia is from Madison, Alabama, and went to school at the University of Alabama at Birmingham (go Blazers!). She graduated in April 2016 summa cum laude with a B.S. in molecular biology and a minor in chemistry. As an undergraduate, Olivia worked in Dr. […] -
March 31, 2016
Nanodiagnostics allow patients to monitor their own health at home
Patients who are discharged after an operation are at risk for complications such as infections and blood clots. A simple molecular test designed for patients to monitor their own health at home may significantly improve how post-operative complications are managed. In collaboration with the Bhatia lab at MIT, we developed a sustained-released formulation of nanoparticles […] -
March 31, 2016
Ian and Quoc awarded Honorable Mention by NSF
Congratulations to Ian Miller and Quoc Mac for being named Honorable Mention by the NSF Graduate Research Program! -
November 20, 2015
Ian Miller and Jason Weis selected for the Petit Research Scholars Program
Congratulations to Ian for being selected a Petit Mentor, and Jason a Petit Undergraduate Scholar for 2016!From the Petit Institute for Bioengineering and Bioscience, "The Petit Undergraduate Research Scholars program is a competitive scholarship program that serves to develop the next generation of leading bioengineering and bioscience researchers by providing a comprehensive research experience for […] -
October 13, 2015
LSI awarded Immunoengineering seed grant
LSI is among five new teams of Georgia Tech and Emory researchers that have been selected for foundational support through the Immunoengineering Seed Grant program, which is led by the Georgia Research Alliance (GRA). In collaboration with Dr. John Altman at Emory, LSI will develop massively parallel technologies to measure and monitor the immune response. Read more […] -
September 29, 2015
Mathematical framework for activity-based biomarkers
Our work examining the use of activity-based biomarkers for early cancer detection has been published in PNAS.Summary | The discovery of cancer at an early stage improves treatment outcomes, yet cancer detection thresholds based on blood biomarkers shed by small tumors lack predictivity. We develop a mathematical framework to explore the use of activity-based biomarkers for […] -
September 29, 2015
LSI welcomes BME graduate student Quoc Mac
Quoc grew up halfway around the world in Saigon, Vietnam. Due to his love for computer games, he studied Computer Science at the University of Science for two years before his family immigrated to the US and settled in North Carolina. Quoc then transferred to the University of North Carolina at Chapel Hill where he […] -
May 27, 2015
Genetically engineered probiotics detect cancer from urine
From Science Daily, "Engineers have devised a way to detect cancer that has spread to the liver, by enlisting help from probiotics -- beneficial bacteria similar to those found in yogurt. Using a harmless strain of E. coli that colonizes the liver, the researchers programmed the bacteria to produce a luminescent signal that can be […] -
March 31, 2015
Shreyas Dahotre named NSF graduate fellow
Congratulations to Shreyas for being selected as the first grad student from LSI for the NSF fellowship! -
September 18, 2014
MIT Koch Institute Special Symposium: Bridging the Gap in Ovarian Cancer 2014
From the Koch Institute, “On September 16, 2014, the Koch Institute for Integrative Cancer Research at MIT hosted Bridging the Gap in Ovarian Cancer, a special symposium for ovarian cancer patients, survivors, family members, advocates, researchers, and other interested members of the public. This free public event was organized by the Koch Institute to share […] -
September 1, 2014
BME graduate students Shreyas Dahotre and Ian Miller join LSI
Shreyas completed his B.S.E. in Biomedical Engineering at Duke, and Ian majored in Chemistry at Furman University. Learn more about them here. Welcome! -
August 15, 2014
Laboratory for Synthetic Immunity launches
Dr. Kwong officially launches the Laboratory for Synthetic Immunity (LSI) in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory School of Medicine. LSI focuses on developing transformative biomedical technologies for engineering human immunity. Read more about LSI’s research here. -
April 11, 2014
MIT Deshpande Center IdeaStream 2014
The MIT Deshpande Center IdeaStream symposium gathers together the leading minds in innovation and entrepreneurship for an invitation-only event each spring. Top-name venture capitalists, successful entrepreneurs, and MIT researchers consider this a must-attend event. Watch Dr. Kwong’s seminar on synthetic biomarkers below: -
March 1, 2014
Press coverage on our paper tests for global health
MIT News: A paper diagnostic for cancer FOX News: Simple paper urine test may detect cancer, blood clots Science News: Urine test detects not pregnancy but cancer Wired: Get an injection, pee on a stick, get a cancer diagnosis Gizmodo: New paper-based urine tests could detect cancer and heart disease Medical News Today: Cheap urine […] -
February 24, 2014
Our work on paper-based urine diagnostics published in PNAS
Summary: Noncommunicable diseases, including cardiovascular disease and cancer, are growing worldwide but are challenging to diagnose because biomarkers that can accurately detect in patients are scarce. We designed nanoparticles to reveal the presence of disease by producing a biomarker in urine that can be detected using paper strips similar to a home pregnancy test. This […] -
October 27, 2013
2013 Career Award at the Scientific Interface
Dr. Kwong was selected for the 2013 Career Award at the Scientific Interface (CASI) from the Burroughs Wellcome Fund. Thank you BWF and the selection committee! -
October 27, 2013
Select press on our urine test to detect blood clots
The Economist: Particle Physiology The Huffington Post: Test to detect hidden blood clots on the horizon ACS Press Room: Toward a urine test for detecting blood clots MIT News: Finding blood clots before they wreak havoc AzoNano: Blood clots chop peptides added onto nanomaterials Medical News Today: Nanotechnology urine test could detect deadly blood clots Health Central: Urine test could […] -
October 20, 2013
MIT Deshpande Center innovation grant
We are 1 of 12 teams awarded an innovation grant by the MIT Deshpande Center, supporting the commercialization of our synthetic biomarker technology! Twelve Research Teams Receive $949, 764 to Develop New Technological Innovations -
September 9, 2013
Our urine test for blood clots published in ACS Nano
Summary: Thrombin is a serine protease that plays a critical role in the formation of obstructive blood clots, or thrombosis, that is a life-threatening condition associated with numerous diseases such as atherosclerosis and stroke. To detect thrombosis in living animals, we design nanoparticles to sense the activity of thrombin by producing a signal in urine for […] -
May 24, 2013
Gaya Murugappan receives cum laude honors
Congratulations to my former trainee and newly minted Harvard MD Gaya Murugappan for receiving cum laude honors for her MD thesis! Best of luck at Stanford! -
May 20, 2013
HHMI Science Meeting
I will be presenting a poster at the HHMI Science Meeting at Janelia Farm on my work on synthetic biomarkers. Should be a week of terrific talks! -
March 27, 2013
Patent issued
Our patent application for our work on synthetic biomarkers has been issued! US patent No: 8,673,267 -
March 12, 2013
Patent: DNA-encoded pMHC tetramers
My PhD colleagues and I have just been awarded a patent for our invention of DNA-encoded pMHC tetramers! U.S. Patent No: 8,394,590 -
March 10, 2013
Omar Abudayyeh named a Soros Fellow
Congrats to my former UROP and current Harvard MD/PhD candidate Omar Abudayyeh for being named a Soros Fellow! -
January 20, 2013
Patent: DNA-encoded Antibody Libraries
A patent has been granted for my work at Caltech on DNA-encoded Antibody Libraries! US Patent No: 8,354,231 -
October 16, 2012
Synthetic biomarkers identify early cancer
Dr. Kwong’s paper describing how nanoparticles can be used as ‘synthetic biomarkers’ to noninvasively monitor liver fibrosis and detect early stage cancer has been published in Nature Biotechnology. Cheers to all my colleagues and collaborators – we formed a great team! Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease, Nat. Biotechnol. Media Coverage: MIT news: New technology […]