Our work in collaboration with Dr. Peng Qiu's group on a computational method to select libraries of promiscuous substrates that can classify mixtures of proteases was published in Cell Reports Methods! Congratulations to Brandon and the team! Read the full manuscript here.

Congratulations to Sofia and Elif for winning President’s Undergraduate Research Salary Awards (PURA) for Spring 2023! PURA funds student salaries to conduct undergraduate research with Georgia Tech faculty and offsets travel expenses for undergraduates to present their research at professional conferences. Read more about PURA here.

Leonard “Lenny” Rogers joins LSI as a new post-doc. Lenny is from Kansas City, Missouri, and completed his Ph.D. at Washington University in St. Louis, where he developed an intracellular arginine sensor to track resistance to arginine deprivation therapy and discovered an important new mechanism of resistance to this therapy working with Prof. Brian Van […]

Dr. Gabe Kwong is the first faculty member at Georgia Tech to be awarded the prestigious NIH Director’s Pioneer Award! This award is the NIH’s largest grant in the High-Risk, High-Reward Research program and will provide LSI $5.5 million over the next five years to, in the words of Dr. Kwong, “develop a living sensor […]

LSI is excited to welcome new graduate students Chloé Thiveaud, Eric Lee, Jamey Siebart, and Sean Chan! Chloé completed her bachelors at Georgia Tech while working as an undergraduate researcher in LSI. Eric graduated from UC Berkeley and worked on CAR T cell therapy at City of Hope before joining LSI. Jamey received a B.S. […]

The National Institute of Biomedical Imaging and Bioengineering at the National Institute of Health is funding a collaborative project led by LSI and Dr. Stanislav Emelianov’s Ultrasound Imaging and Therapeutics Research Laboratory. In this project, we will engineer gold nanorod labeled CAR T cells to track delivery of CAR T cells to tumors, remotely activate […]

Aparna was born in Chennai, India, and grew up in Atlanta, GA. She graduated with a B.S. in Biomedical Engineering from Georgia Tech and is currently enrolled in the Masters of Biomedical Innovation and Development program at Georgia Tech. As an undergrad, Aparna was involved with several Global Health projects, where she designed solutions for […]

Cindy grew up in Hefei, China. She graduated with a B.S. in Biological Sciences from the University of California, Davis, and a M.S. in Environmental Sciences from Emory University. As a graduate researcher in Dr. Eri Saikawa’s lab, she studied heavy metal soil contamination and developed phytostabilization methods for lead remediation. Upon graduating, she worked […]

Our work on multiplexed protease activity sensors conjugated to checkpoint antibodies to discriminate early responses and resistance to immune checkpoint blockade was published in Nature Biomedical Engineering! Congratulations to Quoc, Anirudh, and the team! Read the full manuscript here. Summary | Since 2014, the FDA has approved 7 immune checkpoint inhibitors, but not all patients […]

Our work on antigen-presenting nanoparticles that allow rapid ligand exchange for mRNA delivery to multiple antigen-specific T cells in vivo was published in Science Advances! Congratulations to Ida and the team! Read the full manuscript here.

Congrats to the now-Dr. Brandon Holt, who successfully defended his thesis entitled “Activity-based molecular circuits for programmable medicine” in front of his committee, friends, and family!

Our work on mathematical modeling to predict prodrug escape and treatment success of protease-activated antibacterial prodrugs was published in Molecular Systems Biology! Congratulations to Brandon and the team! Read the full manuscript here.