Patients who are discharged after an operation are at risk for complications such as infections and blood clots. A simple molecular test designed for patients to monitor their own health at home may significantly improve how post-operative complications are managed. In collaboration with the Bhatia lab at MIT, we developed a sustained-released formulation of nanoparticles that are designed to be administered beneath the skin, and report the risk of bacterial infections or blood clots days after discharge. The detection signals are produced in the patients’ urine and detected by inexpensive paper tests. This at-home test may allow patients to monitor their own health during high-risk periods after surgery.
Read the full research study published in Advanced Functional Materials titled “Sustained-release synthetic biomarkers for monitoring thrombosis and inflammation using point-of-care compatible readouts“