Protease circuits for processing biological information published in Nature Communications

Our work on engineering biological circuits was published in Nature Communications! Congratulations to Brandon and the team! Read the full manuscript here.

Summary | Biological circuits engineered to interface with living systems will enable new applications for programmable immune therapies and diagnostics. In this study, we explored how treating proteases as ‘biological bits’ could be used to design cell-free biocircuits with the capacity to perform digital operations such as analog-to-digital conversion for drug delivery, as well as analog operations that implement ‘fuzzy logic’ to solve mathematical problems. 

Press Coverage | Georgia Tech Research Horizons “‘Programmable Medicine’ is the goal for new bio-circuitry research” | | Mirage News | TMR Blog