2013 Career Award at the Scientific Interface
Dr. Kwong was selected for the 2013 Career Award at the Scientific Interface (CASI) from the Burroughs Wellcome Fund. Thank you BWF and the selection committee!
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Select press on our urine test to detect blood clots
The Economist: Particle Physiology
The Huffington Post: Test to detect hidden blood clots on the horizon
ACS Press Room: Toward a urine test for detecting blood clots
Medical News Today: Nanotechnology urine test could detect deadly blood clots
Health Central: Urine test could find blood clots early
HealthLine: Simple urine test spots dangerous blood clots
Health Central: Urine test could find blood clots early
HealthLine: Simple urine test spots dangerous blood clots
MIT Deshpande Center innovation grant
We are 1 of 12 teams awarded an innovation grant by the MIT Deshpande Center, supporting the commercialization of our synthetic biomarker technology!
Our urine test for blood clots published in ACS Nano
Summary: Thrombin is a serine protease that plays a critical role in the formation of obstructive blood clots, or thrombosis, that is a life-threatening condition associated with numerous diseases such as atherosclerosis and stroke. To detect thrombosis in living animals, we design nanoparticles to sense the activity of thrombin by producing a signal in urine for detection using standard clinical methods. We show that signals in urine differentiate between healthy and thrombotic states and correlate closely with the aggregate burden of blood clots formed in the lungs. Our results demonstrate that synthetic biomarkers can be engineered to sense vascular diseases from urine and may allow applications in point-of-care diagnostics.
Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis, ACS Nano
Gaya Murugappan receives cum laude honors
Congratulations to my former trainee and newly minted Harvard MD Gaya Murugappan for receiving cum laude honors for her MD thesis! Best of luck at Stanford!
HHMI Science Meeting
I will be presenting a poster at the HHMI Science Meeting at Janelia Farm on my work on synthetic biomarkers. Should be a week of terrific talks!
Patent issued
Our patent application for our work on synthetic biomarkers has been issued! US patent No: 8,673,267
Patent: DNA-encoded pMHC tetramers
My PhD colleagues and I have just been awarded a patent for our invention of DNA-encoded pMHC tetramers! U.S. Patent No: 8,394,590
Omar Abudayyeh named a Soros Fellow
Congrats to my former UROP and current Harvard MD/PhD candidate Omar Abudayyeh for being named a Soros Fellow!
Patent: DNA-encoded Antibody Libraries
A patent has been granted for my work at Caltech on DNA-encoded Antibody Libraries! US Patent No: 8,354,231